REVEALING RNA DRUGS
Charting the frontier of RNA-modulating small molecules
Focused on patients
Driven by discovery
Base4 is redefining RNA-targeted therapeutics through novel small molecule modulation to go after previously untreatable diseases. Powered by our revolutionary structure-based discovery platform, we are solving complicated diseases in several disease areas including neurology, oncology, and rare diseases.
...and others
Exploiting RNA
structural dynamics
RNA structure wiggles and jiggles, forcing drug hunters to rely primarily on phenotypic methods
Base4 addresses RNA targets with a true structure-based approach
We leverage our proprietary DART Platform, a unique discovery platform that resolves dynamic atomic-resolution structures of RNA targets and screens for selective molecules against druggable RNA regions
Partnering
In addition to our internal programs, we are engaged in strategic collaborations with like-minded pharma groups to accelerate the development of medicine.
Learn more about our partnership philosophy and the advantages of working us.