Focused on patients
Driven by discovery
Base4 is redefining RNA-targeted therapeutics through novel small molecule modulation to go after previously untreatable diseases. Powered by our revolutionary structure-based discovery platform, we are solving complicated diseases in several disease areas including neurology, oncology, and rare diseases.
RNA structure wiggles and jiggles, forcing drug hunters to rely primarily on phenotypic methods
Base4 addresses RNA targets with a true structure-based approach
We leverage our proprietary DART Platform, a unique discovery platform that resolves dynamic atomic-resolution structures of RNA targets and screens for selective molecules against druggable RNA regions