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TACKLING CHALLENGING DISEASES WITH AN ARSENAL OF MECHANISMS ENABLED BY RNA

we are unrestricted by mechanism of action

By taking a structure-first perspective, Base4 is not limited by any particular mechanism of action or RNA type. We have successfully targeted microRNAs, mRNA, pre-mRNAs, repeat expansion RNA (and more) utilizing mechanisms including but not limited to inhibition of translation, inhibition of maturation, and splicing modulation. 

SOME FOCUSED DISEASE AREAS

Paraplegic Sporting Event
Paraplegic Sporting Event
Neuromuscular
Image by National Cancer Institute
Image by National Cancer Institute
Oncology
Old Lady
Old Lady
Neurodegenerative
Baby Stethoscope
Baby Stethoscope
Cardiovascular
Image by Towfiqu barbhuiya
Image by Towfiqu barbhuiya
Immunology
Anchor 3
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